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A possible explanation is that the reduction in ADC is caused by a decline in renal perfusion, GFR or TKV

And now we know it also prevents seizures via the same mechanism

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81,82 A meta-analysis of 15 studies with a total of 7,466 men found genetic mutations (commonly known as single nucleotide polymorphisms or SNPs [pronounced snips]) affecting the methylenetetrahydrofolate reductase (MTHFR) gene that regulates folate metabolism were associated with an increased risk of male infertility

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