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When hydroxocobalamin is given in high doses (such as during cyanide poisoning treatment), unique effects can be observed: patients often experience a transient reddening of the skin or mucous membranes and a reddish discoloration of the urine due to drug excretion

Conversely, this auto-oxidation, which is detrimental to the nitrosothiol formation, contributes to the production of highly reactive peroxynitrite resulting from the reaction between superoxide anions and NO

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Minimizing Oxidative Stress in the Lens: Alternative Measures for Elevating Glutathione in the Lens to Protect against Cataract