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Wang X, Liu L, Qi L, Lei C, Li P, Wang Y, et al

doi: 10.1371/journal.ppat.1004045 163 ChenYHDuWHagemeijerMCTakvorianPMPauCCaliAet al

In initial animal studies, that elucidated the role of glucose metabolism in insulin secretion, the rodent GLUT2 transporter was identified as the major sensor and transporter of glucose in pancreatic -cells

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This reprogramming transforms CAFs into active accomplices that drive chemotherapy resistance and promote pathological stromal remodeling [98, 190]