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Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model

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Treatment always begins at 0.75mg for the first four weeks as a starter dose to allow the body to adjust and minimize gastrointestinal side effects

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569,570 These facts will necessitate further improvements in PROTACs to increase their efficacy and target specificity

En estudios en animales los efectos se observan en das