Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, characterized by an excessive hepatic fat accumulation in the absence of alcoholic abuse, steatogenic medications or others concomitant liver diseases (2)
The quality of the phospholipids used in the liposomal structure directly impacts the supplement's effectiveness
IV delivery maximizes effectiveness : Intravenous administration achieves 100% bioavailability compared to oral supplements' 2-10% absorption rate for both compounds
However, it was also suggested that the association DOXGSH significantly decreased the antineoplastic effectiveness of DOX in a dose-dependent manner, thus proving a disadvantageous effect of GSH use [32]
doi: 10.1139/bcb-2018-0189
[PMID: 33026101 DOI: 10.1111/eci.13423] [DOI] [PMC free article] [PubMed] [Google Scholar] 2.Gavriatopoulou M, Korompoki E, Fotiou D, Ntanasis-Stathopoulos I, Psaltopoulou T, Kastritis E, Terpos E, Dimopoulos MA