Clinical evidence supports its use across the spectrum of disease severity, from newly diagnosed patients to those with longstanding diabetes inadequately controlled on multiple oral agents or basal insulin
Preclinical observations include: Reduction in pro-inflammatory cytokines such as interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-) in animal models Potential effects on immune cell function and inflammatory signalling cascades Possible protective effects in models of inflammatory disease However, there is currently no robust clinical evidence supporting the use of GLP-1 receptor agonists for rheumatoid arthritis specifically
Beyond these concerns, theres now a family ranging from single to triple G-agonists and we have no idea how such potent interventions should be optimally used
B12 Injections Is your slow metabolism a problem
Curcumin, an anti-inflammatory compound found in turmeric, has been shown to increase secretion of GLP-1 and support weight loss and glucose control for those with type 2 diabetes
Every evening I take a dose of gel glutathione before bed