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This suggests that GLP-1 RAs may directly influence these areas, thereby affecting emotional and behavioral states [81]

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Some of the most commonly mentioned symptoms included: Fatigue and low energy Chills Hot flashes Temperature sensitivity Menstrual cycle changes Sleep disturbances Researchers emphasized that these reports do not confirm a direct connection between the medications and the symptoms

Furthermore, such a retrospective design inherently limits the identification of causal relationships, and unmeasured residual confounding variablessuch as glycemic control, hypoglycemic episodes, familial suicide history, and socioeconomic statusmay persist