Were excited about how SENVELGO is changing the way we manage this condition, so we spoke with Dr Rachel Korman, feline internal medicine specialist and co-author of the SENVELGO Patient Management Guide, about why this treatment is such a significant step forward
Mechanisms that control dimorphism are still poorly understood
This dual activation may provide additional metabolic benefits for patients with insulin resistance or metabolic inefficiency, though response depends on individual genetics and baseline metabolic function
Pre-exposure treatment with Adintrevimab led to a neutralizing titer concentration 90 days after administration, which equated to a 70% clinical efficacy rate
Glucagon is typically stimulated by the fall in insulin during fasting in concert with low glucose levels, and responds to hypoglycaemia by mobilising hepatic glucose through the stimulation of glycogenolysis and gluconeogenesis (46)
Because these hormonal transitions introduce high variability and unique metabolic challenges that are difficult for standard clinical guidelines to address, AI may help customize treatment and reduce side effects