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Interactions with negative regulators (MDM2/MDM4) Wild-type p53 interacts with its negative regulators, which mainly include MDM2/4 (Fig

Some exploratory research for neurodegenerative diseases, inflammatory bowel disease etc but evidence is preliminary

Lechuga-Ballesteros D, Abdul-Fattah A, Stevenson CL, Bennett DB

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

S., Manninen, M., & Egan, B

All three metabolites measured in the ACC were significantly lower in the group with residual schizophrenia than in the control group