how was glp-1 discovered Discovery of GLP-1–Based Drugs for the Treatment of Obesity glp-1 drugs history Historical timeline

The primary outcome was to evaluate the safety and tolerability of LY3437943 and the secondary outcomes were the pharmacokinetics and pharmacodynamics of the medication

A Better Question to Ask Yourself Instead of only asking: How do I lose weight faster

The gut microbiome may also undergo changes during GLP-1 therapy, though research in this area remains preliminary

doi: 10.1172/JCI88878

Shared mechanistic pathways of glucagon signalling: Unlocking its potential for treating obesity, MASLD, and other cardio-kidney-metabolic conditions

The most common complaints are nausea, constipation, headache, insomnia, and a bump in blood pressure and heart rate and nausea is actually the top reason people stop taking it