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GLP-1 neurons in the nucleus of the solitary tract project directly to the ventral tegmental area and nucleus accumbens to control for food intake

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Every peptide has its strengths for different research projects

Oral GLP-1 therapies emerged as game-changers: Rybelsus (oral semaglutide) was approved for diabetes in 2019, and in December 2025 the FDA approved Wegovys first oral pill (25 mg semaglutide) for obesity ( [35] )