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they can adjust your dosing schedule, recommend supportive medications, or modify your formulation to improve tolerability

If reconstituted material must be stored, aliquoting into small single-use portions and freezing at minus twenty degrees Celsius or lower can extend stability, though this approach requires validation to ensure maintained potency through the freeze-thaw process

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Compounded drugs are prepared by state-licensed pharmacies following state and federal guidelines but are not FDA-approved or evaluated for safety or effectiveness

Additionally, we find that the decrease in glutamate brought by acivicin could be rescued by administration of pyroglutamate (5-oxoproline), a downstream metabolite in the glutathione pathway that is a precursor of glutamate (Fig