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Below, clinicians and researchers share insights on the neurological, behavioral, and emotional shifts they've observed and why many believe GLP-1s could play a meaningful role in addiction treatment and recovery support

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People with any of the following conditions should not take semaglutide: A personal or family history of medullary thyroid carcinoma A personal history of multiple endocrine neoplasia syndrome type 2 An allergic reaction to semaglutide or any of its ingredients Pregnant women 6

Preclinical studies suggest GLP-1 receptor signaling can modulate sympathetic outflow and peripheral thermoregulatory responses, although direct human evidence remains limited