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Many PlexusDx patients discover they carry genetic variants associated with reduced GLP-1 receptor sensitivity, which immediately justifies a switch to tirzepatide (which activates both GLP-1 and GIP receptors) or to a dual-compound protocol for enhanced metabolic effect

Dehydration : Vomiting or diarrhea from semaglutide, combined with the frequent bowel movements associated with orlistat, could lead to dehydration

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[DOI] [PubMed] [Google Scholar] Niziol J., Ossolinski K., Ossolinski T., Ossolinska A., Bonifay V., Sekula J., Dobrowolski Z., Sunner J., Beech I., Ruman T

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