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Acknowledgements Supported by the Consejo Nacional de Ciencia y Tecnologa (CONACyT): Grant SALUD-2002-C-01-7615/A-1, Fellowship register no

To summarize, although very potent IRAP inhibitors have been discovered after systematic alterations starting from Ang IV none of the compounds are expected to reach the brain, at least not after oral administration

Do these medications cause dry mouth Yes

Rare but serious: seizures (mainly in people with seizure disorders), severe allergic reaction with swelling or trouble breathing

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Muscle loss needs to be managed through exercise and increased protein intake