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In patients treated with GLP-1RAs and tirzepatide, gastrointestinal side effects such as nausea and vomiting are common but do not significantly contribute to weight loss

Foods to Eat with GLP-1 Medications GLP-1 medications like Semaglutide and Tirzepatide can reduce calorie intake by 16% to 39%, but your diet plays a key role in maximizing their benefits

This can sometimes be attributed to the profound changes in the brains reward system-the blunting of food pleasure can occasionally extend to other sources of joy

Hypoglycemia Symptoms: If you're taking these medications alongside insulin or sulfonylureas, contact your provider if you experience repeated episodes of low blood glucose (below 70 mg/dL) or symptoms such as shakiness, sweating, confusion, or rapid heartbeat

On an empty GLP-1 stomach, this often triggers nausea and heartburn

Like liraglutide, semaglutide incorporates an Aib substitution at the 8th position in place of Ala, which confers resistance to enzymatic degradation by DPP-4