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Alternative lengthening of telomeres: DNA repair pathways converge

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Steatoepatite metabolica (MASH) Solo semaglutide ha approvazione FDA Semaglutide ESSENCE (NEJM 2025) Tirzepatide SYNERGY-NASH (NEJM 2024) Verdetto: entrambi mostrano risultati istologici molto buoni nella MASH con fibrosi, ma solo la semaglutide ha ottenuto unapprovazione regolatoria (FDA, agosto 2025)

The controlled attenuation parameter (CAP) decreased significantly: with 1200 mg, the estimated adjusted mean difference was 23 dB/m (95% CI: 41 to 5

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