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Science 366:10131021 Li B, Cao Y, Meng G et al (2019a) Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway
Oxidative stimulation of glutathione synthesis in Arabidopsis thaliana suspension cultures
For Study 5, the primary efficacy parameter was mean percent change in body weight from randomization (Week 20) to Week 68
Persistent activation of these pathways leads to calcium leakage from the ER, mitochondrial dysfunction, and caspase-dependent apoptosis
