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These are one of, if not the most rigorously studied class of peptides ever, with many large, placebo-controlled, randomized trials that followed over the past twenty years from the original GLP-1 drugs such as exenatide, approved by the FDA in 2005

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Vigorous agitation is avoided across peptide research generally because it can shear peptide bonds and degrade the compound before it's even used

SubQ injections have a moderate pace

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