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GHRH (Growth Hormone-Releasing Hormone) analogs (e.g., tesamorelin): Used to treat lipodystrophy in HIV patients

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[4] The researchers measured two things: how much medication reached the bloodstream (pharmacokinetics), and what side effects occurred at each site

They are given by subcutaneous route due to increased efficacy and the ability to avoid first-pass metabolism

Conversely, patients with IBS-C (constipation-predominant) may experience worsening symptoms when using these medications