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2026 Mar 11;148(9):10225-10240

however, a statistically significant difference was noted within the restricted psychiatric population (refer to Figure 4C)

Despite the novelty of this study, several limitations exist

Scientific Overview A synthetic 13-amino acid linear melanocortin analog studied for receptor binding affinity, melanin production pathways, and signaling activity in research models

Thus, drugs targeting the Y220C mutation could stabilize p53 in its proper folded state and restore its wild-type function by binding to these pockets