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Clinical trials demonstrated average weight reductions of 15-21% of body weight over 72 weeks in people with obesity (SURMOUNT-1), while more modest weight loss was observed in type 2 diabetes patients (SURPASS trials)

Given these drugs inhibit dopamine reception from foods, alcohol and other cravings it seems highly likely they will blunt other emotions too

On both sites, the vast majority of complaints relate to the companys cancellation policy coming as a surprise to users who wish to cancel

From a clinical effectiveness standpoint, irregular adherence may undermine the medication's ability to provide sustained benefits

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