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While side effects are possible, most are mild and manageable with proper care and technique

5 Refrigerate unopened vials until use

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Using a model of induced DSBs 28 , we found increased DSBs and delayed repair following suppression of KG using the IDH1 inhibitor, which was rescued by KG, l-carnitine and acetylcarnitine (Fig

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Notably, the direction of lipolytic modulation may depend on the metabolic context and experimental setting: in insulin-resistant states, semaglutide can improve insulin-mediated suppression of pathological basal lipolysis, while in mechanistic in vitro systems it may enhance stimulated lipid mobilization coupled to increased fatty acid oxidation and downstream metabolic remodeling