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But with so many supplements on the market making the same promises, it's hard to know what's actually worth trying, or why some products work and others don't

The field currently lacks the application of standardized approaches for microbiota modulation, like FMT and precision nutrition, which further hinder reproducibility and clinical application (Lu et al., 2024)

The molecular mechanism underlying the different responsiveness of these ShHTLs and ShD14 remains vague

Some examples include certain opioid analgesics and anesthetics: MB given with opioid pain medications like oxycodone or morphine requires caution, as there have been reports of enhanced CNS depression or other additive effects (partly because some opioids also increase serotonin or have monoaminergic effects)

Glutamate acts as a neurotransmitter in the brain