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Why this matters 1 Efficacy arms race in obesity Zepbound previously showed superior outcomes Wegovy 7.2 mg narrows the gap Competition now driven by clinical performance 2 Massive market at stake Obesity = one of the largest pharma markets globally Prescriber preference shifting toward higher efficacy Market share highly sensitive to outcomes 3 Faster FDA pathway signal First GLP-1 approved under FDAs national priority voucher program Accelerated review (12 months) 4 Global rollout underway EU/UK approvals already in place (7.2 mg) U.S

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Shelf life for properly stored lyophilized powder is 24 months