The polyphenols contain work to calm redness from sun exposure and reduce swelling caused by breakouts
This selectivity proves critical for ACI applications, where maintaining viable cell numbers remains essential for therapeutic success
However, at high concentrations, when RNS levels exceed the capability of its detoxification in the biological system, serious damage to cells may occur [147, 148] due to inhibition of mitochondrial respiratory function by competing with O 2 for interaction with cytochrome oxidase [149] and via nitrative/nitrosative stress [150, 151]
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