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Methylcobalamin has some metabolic and therapeutic in applications not shared by the other forms of vitamin B12

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L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials

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27, 28 The tumor cells of desmoplastic melanoma decorate with antibodies to S100 protein in an almost ubiquitous fashion, 6 with antibodies to neuron-specific enolase in 4096% of cases, 6, 17 and with HMB-45 in roughly 20% of cases 6 (Figure 7)