Your physician will design a protocol tailored to your response and long-term goals
However, patients taking Ozempic alongside metformin may be at risk due to metformin's documented interference with B12 absorption in the terminal ileum
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Insulin Dose Reduction at GLP-1 RA Initiation In the SUSTAIN-5 trial (N=397), patients on semaglutide 1 mg plus basal insulin experienced a symptomatic hypoglycemia rate of 11.3%, versus 1.1% in the semaglutide-plus-metformin-only arm [6]
Experienced practitioners will perform lab tests to get a baseline, and optimize levels from there
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