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Indirect markers include elevated oxidative stress markers, poor recovery from exercise, chronic fatigue, weakened immune function, or elevated liver enzymes

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It causes sharp, timed GH pulses without impacting cortisol or prolactin levels

It has been widely reported that an exercise bout consisting of eccentric muscle contractions can result in substantial damage to the contractile unit, which often results in inflammation, loss of Ca 2+ homeostasis and possibly induction apoptosis as a result