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PMCID: PMC8078152

The therapy can benefit eczema symptoms, improve hydration to tackle dryness and promote skin elasticity

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Impact on Blood Glucose Control: For patients with type 2 diabetes, tirzepatide significantly improves glycemic control by enhancing glucose-dependent insulin secretion and suppressing inappropriate glucagon release

Glucagon receptor agonism in isolation raises blood glucose which is why glucagon was historically viewed as problematic in metabolic disease but when co-activated alongside GLP-1 and GIP signaling, the glucose-raising effect is offset while the energy-expenditure effect is preserved

doi: 10.1007/BF00314926