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Multiple Sclerosis and Related Disorders, 27 , 52-60

Once activated, these microglia release ROS, inflammatory cytokines, and chemokines (Thakur et al., 2023), initiating a chronic inflammatory response and enhancing the synthesis of cathepsin B protein ( 4.2 Diabetes Oxidative stress not only directly harms islet beta cells but also acts as a signaling molecule that activates various stress-sensitive pathways

Done safely = start low, watch IGF-1 and glucose like a hawk, stay medically supervised, no heroics

doi: 10.1089/ars.2010.3496 86 LevringTBHansenAKNielsenBLKongsbakMvon EssenMRWoetmannAet al

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When your body is dehydrated enough to reduce saliva production, it is also diverting water away from the colon, hardening stool