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Individual protocols must be personalized based on body composition, metabolic status, and physician assessment

While the clinical presentation of THMD5 varies, affected individuals often experience episodic ataxia, dystonia, and lactic acidosis (123)

Polysulfide stabilization by tyrosine and hydroxyphenyl-containing derivatives that is important for a reactive sulfur metabolomics analysis

One limitation of this approach is that medications with substantially different adverse event profiles may generate ratios that do not entirely capture their true visual impairment risk

While results were somewhat beneficial for certain subgroups, the overall effects were not statistically significant, indicating that more robust studies are needed

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