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Phentermine can also cause gastrointestinal disturbances, including dry mouth, constipation, and altered taste
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A phase 2 trial assessing mazdutide 3, 4.5 and 6 mg in a Chinese population with overweight/obesity demonstrates up to 11.3% WL after 24 weeks of treatment compared to 1% weight gain with placebo [70]
Many highlight the quick responses and easy access to care as key benefits
Cladribine, gemcitabine, lovastatin, and tamoxifen overall have lower IC 50 than the NO-based drugs, which are part of a few cancer and melanoma clinical trials (NCT00060710, NCT05502900) and pronouncedly reduced viability in both, metastatic and therapy-resistant melanoma cell lines (see Supplementary File 1)
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