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In fact, autophagy activation was confirmed in U251 and U-87MG cells by the increased levels of ATG12 protein (Fig

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We next asked if a mitochondrial route might be involved since both glucose and fatty acids can feed mitochondrial acetyl-CoA pools (Figure 5A

Likely secondary to increased NAD+-dependent mitochondrial activity

Co-author DiFeliceantonio called the project bittersweet, her last collaboration with Bickel, but one that reflects his drive to translate behavioral science into real-world impact