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Specific molecular mediators, depot/cell-type specificity, and strength of evidence are summarized separately in Table 1

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BMC Neurosci 9:67 Shanker G, Aschner M (2001) Identification and characterisation of uptake systems for cystine and cysteine in cultured astrocytes and neurons: evidence for methylmercury-targeted disruption of astrocyte transport

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Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region

The Wegovy protocol, the FDA-approved formulation for weight loss, uses this progression: 0.25mg for weeks 1 through 4, 0.5mg for weeks 5 through 8, 1.0mg for weeks 9 through 12, 1.7mg for weeks 13 through 16, and finally 2.4mg from week 17 onward