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[DOI] [PubMed] [Google Scholar] 68.Karakasis P, Patoulias D, Fragakis N, Klisic A, Rizzo M

doi:10.1080/01443615.2024.2381569

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Dosage form optimization: Controlled-release formulations enabling once-weekly oral administration Indication expansion: NASH, Alzheimers disease, cardiovascular protection Conclusion: A game-changing Molecule Design Orforglipron represents a triumph in small molecule drug designit demonstrates that clever chemical structure design can break through the dominance of biologics