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Voltage-clamp electrophysiology verifies that the Na + - and carnitine-binding sites are coupled To further explore the carnitine and Na + binding sites, wildtype and mutant OCTN2 transporters were expressed in Xenopus laevis oocytes and two-electrode voltage-clamp electrophysiology was utilised to demonstrate the transport of carnitine is Na + -dependent
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While hailed as a public health success for increasing access to this life-saving drug, this OTC option remains out of reach for people who cannot afford the $45 average price tag for a two-dose box
