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This 80% increase, observed in third-trimester pregnant women was estimated to occur throughout the entire pregnancy.[] This means **43% MORE of the toxic NAPQI metabolite is produced** during pregnancy compared to non-pregnant women

& Zigman, J

These 3 participants received GR alone prior to their GR + Myr supplementation, and this treatment group showed significantly greater GR conversion percentages following each treatment ( p = 0.033 and p = 0.0089, respectively

J Int Neuropsychol Soc 2013;19:873-80

10.1002/hep.22177 47 LeemingM

t-HO-1 has been shown to induce Nrf2 expression, to bind to it favouring nuclear translocation, thus establishing an amplification loop