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Patients Inadequately Controlled on Sulphonylurea (SU) GetGoal-S randomised 859 patients with longer duration diabetes (mean duration of 8.08.5 years) who were inadequately controlled on an SU (85% were receiving metformin in addition to their SU therapy at baseline) to lixisenatide 20 g OD or placebo for 24 weeks, with an optional extension of 52 weeks [21]

Retatrutide is a GLP-1/GIP/glucagon triple agonist originally developed for obesity treatment

In animal studies, target mutation HGF or MET, or both genes caused abnormalities that led to embryonic lethality [42]

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Proteinprotein interaction (PPI) networks were constructed with STRING database ( v.10.5) and visualized with the visNetwork R package

[Google Scholar] Park EY, Shimura N, Konishi T, Sauchi Y, Wada S, Aoi W, et al