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The genuine human Phase II trials used full-length thymosin beta-4 as a topical eye drop for dry eye, and even those had mixed results on their primary endpoints

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doi: 10.1371/journal.pmed.1001747 303

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It is important to note that intestinal dysbiosis has also been demonstrated to encourage RA pathogenesis further emphasising the ability of gut microbes to influence human health (Asquith et al

(2003) Journal of Clinical Endocrinology & Metabolism n=120 Phase 2 double-blind trial of AOD 9604 5mg daily versus placebo in obese subjects measuring weight loss and lipid changes