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Buse JB, Wexler DJ, Tsapas A, Rossing P, Mingrone G, Mathieu C, et al

The dosing schedule is structured to minimise gastrointestinal side effects and to allow the body to adjust to the medication

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Clinical trials of brand-name tirzepatide showed up to 22.5% body weight reduction at the highest dose plus improved cardiovascular and metabolic markers those studies inform how the active ingredient is understood, but the safety, efficacy, and quality data from those trials do not directly apply to compounded preparations