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10.1007/s00418-018-1747-9 41 KumarM

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FDA approvals for weight loss indications have increased use and patient demand for easy-to-use formulations is increasing interest in oral GLP-1 alternatives in addition to the most popular injectables

These conditions include cardiovascular disease (such as coronary artery disease, stroke, life-threatening arrhythmias, congestive heart failure, or untreated hypertension), advanced arteriosclerosis, hyperthyroidism, glaucoma, psychiatric agitation or psychosis, recent or concurrent MAOI therapy (within 14 days), history of drug abuse, pregnancy, breastfeeding, pediatric patients under 16, and concurrent use of other weight-loss medications