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12,15 Until the results of STEP 8 (weekly semaglutide 2.4 mg versus daily liraglutide 3.0 mg) were published in 2022, 16 all randomized controlled trials (RCTs) in the STEP program have compared semaglutide with placebo

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The NTS is an area of the brain associated with visceral reflexes and establishes connections with the hypothalamus to regulate feeding (70, 71)

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