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[24] Several large employers Boeing, Walmart, and a number of state employee benefit plans moved portions of their drug benefit to pass-through PBM models or direct-purchase arrangements during this period

A phase 2 trial found that roughly 35% of the weight loss with semaglutide came from lean mass

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25,26 Effects on Epicardial Adipose Tissue GLP1-RAs decrease the volume of epicardial adipose tissue, which is often elevated in HFpEF and is a source of proinflammatory cytokines and adipokines

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