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That distinction carries three practical caveats worth stating plainly: Dose translation is not one-to-one

ABSORPTION AND BIOAVAILABILITY Oral bioavailability: Unlike some peptides that are degraded by stomach acids, BPC-157 capsules have been found to remain stable when taken orally, allowing them to reach the target tissues effectively

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These overlapping limitations highlight an urgent need for further validation through large-scale, single-strain, long-term follow-up multicenter RCTs

Writing Original Draft: R.G., R.R., N.K., E.S.H., E.F.F

Beyond antimicrobial effects, certain peptides contribute to the integrity of the gut barrier by reducing intestinal permeability, which prevents the translocation of bacterial products that can trigger systemic inflammation