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Due to its roles in such a broad array of systems, targeting the ghrelin receptor with agonists or antagonists will not only affect the phenomenon of interest, such as feeding, but will also affect the other systems in which ghrelin is involved, leading to unwanted side effects

The risk of pancreatitis The risk of pancreatitis There is a risk of patients taking weight loss injections being at an increased risk of an inflamed pancreas

That would materially change long-run dosing math and is worth watching as the Q2 to Q3 2026 TRIUMPH-1 and TRIUMPH-2 readouts arrive

It is an unusual skin sensation burning, tingling, or numbness on the skin