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The study comprised a single intravenous (i.v.) administration of the peptide (20 g/kg in Sprague-Dawley rats and 6 g/kg in beagle dogs), a single intramuscular (i.m.) administration of 20, 100, or 500 g/kg (rats) and 6, 30, or 150 g/kg (dogs), and repeated i.m

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That is a large effect and matches the direction of earlier Phase 2 glucose data, but the magnitude is higher than what has been reported in comparable tirzepatide or semaglutide obesity trials