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They are not effective, have little scientific evidence to back up their claims, and are misleading because they do not contain any GLP-1 agonists
But the theory is supported by basic receptor pharmacology principles that apply across all G protein-coupled receptors
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People using oral contraception should either: Switch to a non-oral method, or Use a barrier method for 4 weeks after initiation and 4 weeks after each dose escalation Given the titration schedule, that can mean several months of backup contraception