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ERG responses identified increased photoreceptor and ON-bipolar cell responses, but reduced OFF-bipolar cell responses, which were correlated with BPA-induced changes in voltage-gated K + and Ca +2 currents recorded from retinal bipolar cells

Haufe S, Kaminski J, Utz W, Haas V, Mhler A, Daniels MA, et al

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In keeping with our previous observation that the trafficking effects of biased GLP-1R agonists tend to exert a more pronounced effect on glucose regulation than on food intake (Jones et al., 2018b), anorectic effects of -phe1 and -asp3 peptides were similar (Figure 6J), although there was a non-significant trend towards reduced efficacy for both -phe1 compounds at early timepoints which was reversed at 8 hours

10.1093/emboj/18.12.3204