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2 Background information The American Urological Association (AUA) describes IC as a disorder manifested by a perceived sensation of pain and pressure related to the bladder and associated with lower urinary tract symptoms of greater than 6 weeks duration, in the absence of infection or other identifiable causes

The peptides intracellular mechanism doesnt have a clear pharmacokinetic basis for split dosing

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However, the absence of human clinical trials means the safety profile in humans is completely unknown

Many experiments assess immediate effects within days to weeks post-administration

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